Injection drug use appears to be the most harmful route of administration.

Which route of drug administration carries the greatest risk to the patient?

Intravenous. The IV route carries the greatest risk of any route of drug administration. By administering directly into the systemic circulation, either by direct injection or infusion, the drug is instantaneously distributed to its sites of action. This route of administration can be complex and confusing.

Which route of drug administration is most likely to lead to the first effect?

Enteral Route of Medication The first-pass effect is an important consideration for orally administered medications. It refers to the drug metabolism whereby the drug concentration is significantly diminished before it reaches the systemic circulation, often due to the metabolism in the liver.

Which route of administration will cause the user to feel the effects the quickest?

Intravenous (IV) Injection straight into the systemic circulation is the most common parenteral route. It is the fastest and most certain and controlled way. It bypasses absorption barriers and first-pass metabolism. It is used when a rapid effect is required, continuous administraction and large volumes.

How many types of routes of administration are there for poison?

Introduction – Routes of Poison Administration The most common examples are oral and intravenous poison administration. Routes of administration of drugs/poisons can also be categorized based on where the target of action is. Action may be topical (local), enteral (system-wide effect) or parenteral (systemic action).

Which of the following are disadvantages of the parenteral route?

Disadvantages of parenteral preparations to the patient include lack of drug reversal, risk of infection and emboli, risk of hypersensitivity reactions, and cost.

What are the 3 main routes of drug administration?

Routes of administration of a drug are determined by its physical and chemical properties, patient characteristics and the rapidity of response desired. Major routes are oral, parenteral and topical.

Which routes of administration can be used to avoid the first-pass effect quizlet?

Alternative routes of administration like, intravenous, intramuscular, inhalational aerosol, transdermal and sublingual avoid the first-pass effect because they allow drugs to be absorbed directly into the systemic circulation.

Which route of drug administration provide a rapid response in a patient?

Background: Parenteral therapy is a route of administration for drugs which are poorly absorbed via the oral route and it can provide a rapid response during an emergency.

Which is faster subcutaneous or intramuscular?

Intramuscular injections are absorbed faster than subcutaneous injections. This is because muscle tissue has a greater blood supply than the tissue just under your skin.

Which of the following routes of administration would deliver the fastest drug effect on the body quizlet?

Which of the following routes of medication administration has the fastest effect? Because its administration is directly into a vein, a drug given intravenously enters the body quickly. The intravenous route is the fastest acting of all the routes of medication administration.

How does route of administration affect toxicity?

Although compounds can be metabolized in the body both from oral and injection routes, first-pass metabolism occurs in oral route but not in injection route. This will result in decrease of toxicity in oral route for most compounds as compared with injection route.

What is the most common method of poison?

Ingestion is the number one route of poisoning in children. Other poisoning can be on the skin, in the eye, inhalation, or bites or stings.

Which of the following modes of administration of poison is the fastest way to feel its effect and considering its 100% bioavailability?

The intravenous route is known to be the fastest way to deliver drugs into the human body and hydrophilic drugs reach 100% of bioavailability.

Which route of drug administration is best?

Intravenous administration is the best way to deliver a precise dose quickly and in a well-controlled manner throughout the body. It is also used for irritating solutions, which would cause pain and damage tissues if given by subcutaneous or intramuscular injection.

Which patient is at highest risk for a drug drug interaction?

Among adults age 65 and older, 40 percent are taking five or more medications. These older adults, who are typically taking multiple medications for multiple conditions, are among those at highest risk for drug interactions, though it is important to note that serious drug interactions can happen to anyone.

What are the 3 main routes of drug administration?

Routes of administration of a drug are determined by its physical and chemical properties, patient characteristics and the rapidity of response desired. Major routes are oral, parenteral and topical.

What are the disadvantages of parenteral feeding?

Complications Associated with Total Parenteral Nutrition Dehydration and electrolyte Imbalances. Thrombosis (blood clots) Hyperglycemia (high blood sugars) Hypoglycemia (low blood sugars)

Why should we avoid the oral route for some drugs?

The subcutaneous route is used for many protein drugs because such drugs would be destroyed in the digestive tract if they were taken orally.

Why IV route is better than oral?

When a medication is administered intravenously it can directly reach the blood circulation and thereby assure 100% bioavailability. To be effective, oral antibiotics must achieve serum bactericidal activity almost comparable to that of its IV counterpart.

Which client has the highest risk for developing medication toxicity?

Risk Factors for Adverse Drug Events Polypharmacy—taking more medications than clinically necessary—is likely the strongest risk factor for ADEs. Elderly patients, who take more medications and are more vulnerable to specific medication adverse effects than younger patients, are particularly vulnerable to ADEs.

What is toxic drug reaction?

Drug toxicity may occur when a person has consumed a dose of a drug that is too high for them to handle. It may also occur when the person’s liver and/or kidneys are unable to function properly and get the drug out of the bloodstream. This can cause it to build up over time until it starts to cause problems.

What are the 4 types of adverse drug reaction?

Adverse drug reactions are classified into six types (with mnemonics): dose-related (Augmented), non-dose-related (Bizarre), dose-related and time-related (Chronic), time-related (Delayed), withdrawal (End of use), and failure of therapy (Failure).

Which of the following drug administration routes is the least affected by first pass metabolism?

Rectal. Rectal administration can be used for producing local or systemic effects. It is quite unreliable however. 75% of drainage of the rectal region bypasses the portal circulation and thus minimizing first-pass effect.

Which of the following is the slowest way for a drug to reach the bloodstream?

Administration by the oral route is the slowest way for medication to reach the body’s cells. The oral route may be referred to as PO or by mouth.

What is the slowest route of administration for a drug quizlet?

Medication routes, from slowest to fastest rates of absorption, are: subcutaneous, intramuscular, sublingual, inhalation, intravenous.